P1: A Review of Neuropsychological Function in Post Traumatic Stress Disorder (PTSD) with Substantial Substance Use Comorbidity

Neuropsychological approach tries to link behavior with brain functions. One of the structural changes and functional disorders that is, post-traumatic stress disorder (PTSD). This impaired memory function, learning, emotional processing and cognitive and structural changes in the brain. Various aspects of neuropsychological function have been reported to be abnormal in (PTSD); however, the majority of these data come from studies of seriously ill, treatment-seeking samples with substantial substance use comorbidity. The article is intended neuropsychological status, structural changes and outcomes through systematic review from 1995 to 2017 to examine. The methodology of systematic review and select papers for controlled studies of sites Med line, Pubmed, Psycho info, Psycholit is from 1995 to 2017. Results showed that PTSD veterans with substantial substance use comorbidity performed more poorly than the comparison sample on a measure of verbal learning, greater sensitivity to proactive interference, and more perseverative errors. Veterans with PTSD diagnoses also evidenced impairments in word fluency and visual attention/tracking abilities. These preliminary findings suggest that diagnoses of chronic PTSD in combat veterans are associated with cognitive performance deficits. (Uddo & et al., 1995).Previous research on the neuropsychology of posttraumatic stress disorder (PTSD) has identified several neurocognitive deficits that co-occur with the disorder. However, it remains unclear whether these deficits are due to trauma exposure, PTSD symptomatology or psychiatric/substance abuse comorbidity. Relationships of neuropsychological functioning to measures of psychiatric symptoms and substance abuse were examined. There were very few significant associations between neuropsychological performance and clinical variables, Neuropsychological impairment may not be an invariant feature of PTSD, but when it is present, it may be associated with poorer functional outcomes. (Vanderkok to the Mirzaee 1387) ,The results of neuropsychological performance in patients with PTSD showed disfunctional emotional structure. (Moradi, et al., 2012, Mac Nelly 2007, Mirzaee 2015). Navarz this study showed that between war and recalls related to memory performance in sixty years later, there is a relapse (Navarez et al., 2017). Identifying adaptive ways to cope with extreme stress and substance use is essential to promoting long-term health. Memory systems are highly sensitive to stress, and combat exposure during war has been shown to have deleterious effects on cognitive processes, decades later .The veterans with PTSD performed more poorly on measures of attention and abstract reasoning/executive function. In general research shows that people with PTSD can reduce damage in the prefrontal cortex and medical response, difficulty paying attention, concentration, memory and reduce the size of the hippocampus and amygdala activity also increased exacerbated fears and thrilling. Cognitive rehabilitation training, CBT treatment, especially exposure therapy, cognitive restructuring and medication can improve memory function and information processing in patients with PTSD.